January is an exciting time around the AICR offices. This is when our newly-funded investigators begin work on their projects, and it’s a reminder to us that scientific research provides the basis for all of AICR’s work. Our grant program is extremely competitive and only the most novel and promising projects make it through our rigorous peer-review process. This year’s funded research grants cover a wide variety of topics but they all focus on how nutrition, physical activity, or obesity is related to cancer, and they are all aimed at preventing cancer and improving survival.
Some of our new investigators work in labs with cell cultures or with animal models, while others work in clinics or on large population studies. You can read about their research in Cancer Research Update.
To learn more about eligibility and criteria for AICR grants, see our Grant Application Package. And if you are a researcher with a great idea for a project, keep an eye out for AICR’s call for applications in the fall. Questions? Contact us at firstname.lastname@example.org.
Thank you to AICR’s generous donors for continuing to support these innovative and important projects.
Susan Higginbotham, PhD, RD, is AICR’s Vice President of Research.
There’s strong research now showing that being active can reduce your risk of colorectal cancer, but how physical activity affects survivors of this cancer is not as clear. Now comes a study suggesting that being active — both before and after diagnosis —can lengthen survival for colorectal cancer survivors.
Not watching a lot of television — a common measure for sedentary living — was also found to improve survival. Survivors who were watching fewer than two hours a day of TV before diagnosis had a reduced risk of mortality compared to those watching five or more hours of TV a day.
The study was published in the Journal of Clinical Oncology last week.
For pre-diagnosis, study authors used data from approximately 3,800 survivors who were part of the large NIH-AARP Diet and Health Study study. In the mid 1990s, the participants were 50 to 71 years old. They answered questionnaires about how much TV they watched, their activity and other lifestyle habits. Those who had developed colorectal cancer were identified in 2006. Continue reading
A new long-term study that adds to the research on diet and breast cancer survival finds that women with certain types of breast tumors who reduced their dietary fat for years after diagnosis — and also lost weight — had lower death rates over the next 15 years than survivors on a standard diet.
The study was presented today at the San Antonio Breast Cancer Symposium and is not yet published in a journal.
It was funded in part by AICR and joins a growing body of research investigating how diet affects women diagnosed with breast cancer. In October, an AICR report on breast cancer survivorship in partnership with WCRF found some indication that fat may play a role in survival. The Continuous Update Project report found there was limited but consistent research suggesting that eating lower amounts of total fat and in particular, saturated fat, before a diagnosis of breast cancer linked to improved survival.
Weight loss may also play a role, as the low-fat group lost a a modest but significant amount of weight in this study. The CUP report found indications that being a healthy weight may lengthen survival for women diagnosed with breast cancer. But the report’s findings were not strong enough to make a specific recommendation.
Observational evidence relating to low-fat diets and breast cancer survival is mixed and previous research from another major randomized dietary study among breast cancer survivors – the WHEL study – found a lowfat diet did not affect mortality or recurrence.
The study presented today included approximately 2,400 women who were part of Women’s Intervention Nutrition Study (WINS), a study that first launched in 1987. All the women were diagnosed with early stage breast cancer and they joined the study within six months of diagnosis. Continue reading