Today, a new study found that replacing even a small amount of that sedentary time with some physical activity could reduce early death for people of all weights and waist sizes. A growing body of research is linking sedentary behavior to cancer risk.
The new analysis, published in American Journal of Clinical Nutrition, used data from over 334,000 people in the European Prospective Investigation into Cancer Nutrition (EPIC) study to determine if overweight, obesity or large waist size would affect whether reducing sedentary behavior improves survival.
The investigators compared rates of mortality over twelve years, between four levels of physical activity (inactive, moderately inactive, moderately active and active) and categorized by BMI and waist size. Continue reading
Research shows that eating high amounts of red meat increases risk of colorectal cancer, possibly because it may spur inflammation. A new animal study published in The Proceedings of the National Academies of Sciences now points to a sugar molecule found in red meat as one mechanism responsible.
The molecule called N-glycolylneuraminic acid, or Neu5Gc for short, sticks to the ends of sugars found in red meats such as beef, pork, and lamb. Although most mammals produce Neu5Gc, humans don’t. Humans are “immunized” against Neu5Gc shortly after birth by an unusual process involving gut bacteria. As a result, when people eat foods that contain Neu5Gc, we produce antibodies that react to Neu5Gc, triggering inflammation.
Previous research has detected relatively high amounts of Neu5Gc in cancerous tissue.
In foods, Neu5Gc can be free or it can be bound to the ends of long sugar chains attached to proteins. The bound form is highly bioavailable, meaning it can easily be taken up into the body’s cells. Neu5Gc tends to accumulate in cells of the colon, prostate, and ovary. Continue reading
A paper published recently in the journal Science has generated an enormous amount of media coverage. The paper’s matter-of-fact title, “Variation in Cancer Incidence Among Tissues Can Be Explained By the Number of Stem Cell Divisions,” doesn’t sound like something that would set the internet buzzing, but it sure did.
That’s because of how the paper was promoted and covered: “MOST CANCERS DUE TO BAD LUCK, NOT PREVENTABLE, STUDY FINDS” screamed one headline. But there’s a sharp disconnect between this paper’s findings and the hype surrounding it.
Here at AICR, we fund and analyze the research showing that a healthy weight, a healthy diet and regular physical activity could prevent hundreds of thousands of U.S. cancers every year. We’re concerned that the oversimplified coverage this study received will reinforce the widespread conviction that cancer “just happens” and cause Americans to throw up their hands and ignore the empowering, evidence-based message that everyday choices play an important protective role in risk for many of the most common cancers.
When looking at this paper, ask yourself three basic questions. Continue reading