Today, a new study found that replacing even a small amount of that sedentary time with some physical activity could reduce early death for people of all weights and waist sizes. A growing body of research is linking sedentary behavior to cancer risk.
The new analysis, published in American Journal of Clinical Nutrition, used data from over 334,000 people in the European Prospective Investigation into Cancer Nutrition (EPIC) study to determine if overweight, obesity or large waist size would affect whether reducing sedentary behavior improves survival.
The investigators compared rates of mortality over twelve years, between four levels of physical activity (inactive, moderately inactive, moderately active and active) and categorized by BMI and waist size. Continue reading
Research shows that eating high amounts of red meat increases risk of colorectal cancer, possibly because it may spur inflammation. A new animal study published in The Proceedings of the National Academies of Sciences now points to a sugar molecule found in red meat as one mechanism responsible.
The molecule called N-glycolylneuraminic acid, or Neu5Gc for short, sticks to the ends of sugars found in red meats such as beef, pork, and lamb. Although most mammals produce Neu5Gc, humans don’t. Humans are “immunized” against Neu5Gc shortly after birth by an unusual process involving gut bacteria. As a result, when people eat foods that contain Neu5Gc, we produce antibodies that react to Neu5Gc, triggering inflammation.
Previous research has detected relatively high amounts of Neu5Gc in cancerous tissue.
In foods, Neu5Gc can be free or it can be bound to the ends of long sugar chains attached to proteins. The bound form is highly bioavailable, meaning it can easily be taken up into the body’s cells. Neu5Gc tends to accumulate in cells of the colon, prostate, and ovary. Continue reading
This year, for the first time, the US Dietary Guidelines committee may recommend that Americans eat less red and processed meat, a key recommendation from AICR for lowering cancer risk. Every five years, the US Dietary Guidelines are updated based on the committee recommendations and they are due out this year.
According to reports from the committee’s most recent discussions, the 2015 nutrition and eating guidelines may also call for Americans to eat more plant foods, like vegetables, fruit, beans and whole grains, also an AICR recommendation. Research shows that eating patterns like this – more plant foods and minimal red meat – can help prevent obesity and chronic diseases like cancer, type 2 diabetes and heart disease.
These 2015 guidelines may also call for lower sodium and specific limits on added sugars.
If enacted, these recommendations will better align with AICR’s Recommendations for Cancer Prevention and could, in the long-term, lead to fewer cancer cases. AICR estimates that about 1/3 of the most common cancer cases every year in the US wouldn’t happen if Americans followed a healthy diet, were physically active every day and maintained a healthy weight.
Guidelines like this will inform dietary advice for individuals, but will also set in motion changes for school lunches and other government food and nutrition programs. Read more about the guidelines at health.gov.