Today, a new study found that replacing even a small amount of that sedentary time with some physical activity could reduce early death for people of all weights and waist sizes. A growing body of research is linking sedentary behavior to cancer risk.
The new analysis, published in American Journal of Clinical Nutrition, used data from over 334,000 people in the European Prospective Investigation into Cancer Nutrition (EPIC) study to determine if overweight, obesity or large waist size would affect whether reducing sedentary behavior improves survival.
The investigators compared rates of mortality over twelve years, between four levels of physical activity (inactive, moderately inactive, moderately active and active) and categorized by BMI and waist size. Continue reading
Research shows that eating high amounts of red meat increases risk of colorectal cancer, possibly because it may spur inflammation. A new animal study published in The Proceedings of the National Academies of Sciences now points to a sugar molecule found in red meat as one mechanism responsible.
The molecule called N-glycolylneuraminic acid, or Neu5Gc for short, sticks to the ends of sugars found in red meats such as beef, pork, and lamb. Although most mammals produce Neu5Gc, humans don’t. Humans are “immunized” against Neu5Gc shortly after birth by an unusual process involving gut bacteria. As a result, when people eat foods that contain Neu5Gc, we produce antibodies that react to Neu5Gc, triggering inflammation.
Previous research has detected relatively high amounts of Neu5Gc in cancerous tissue.
In foods, Neu5Gc can be free or it can be bound to the ends of long sugar chains attached to proteins. The bound form is highly bioavailable, meaning it can easily be taken up into the body’s cells. Neu5Gc tends to accumulate in cells of the colon, prostate, and ovary. Continue reading
Low alcohol consumption and a plant-based diet, part of AICR’s Recommendations for Cancer Prevention, are associated with reducing the risk of colorectal and other obesity-related cancers, finds a new study, adding to a growing body of independent research on how following AICR’s recommendations links to lower cancer risk, longer survival, and improved overall health.
This latest study was published in Cancer Causes & Control. You can read more about the other studies investigating AICR recommendations here.
The Cancer Causes & Control study included almost 3,000 cancer-free adults who had no history of cancer. Participants were part of the ongoing Framingham Heart Study. Back in 1991, everyone filled out a questionnaire about how much they weighed, what they ate and their activity habits.
After almost 12 years, 480 of the participants had developed an obesity-related cancer, such as colorectal or breast.
Study researchers then scored how much participants met seven of AICR’s recommendations, giving them zero, half point or one point. The scoring included Continue reading