AICR’s evidence shows that carrying extra body fat increases risk for 11 types of cancer, including postmenopausal breast and endometrial. Now a new study looking at how long women have overweight and obesity suggests that if women keep their weight steady and/or lose weight – even small amounts – that may help lower risk for several cancers, especially postmenopausal breast and endometrial.
AICR’s evidence shows that having too much body fat increases risk for eleven cancers. But researchers are looking at whether losing weight, once overweight, would lead to lower risk for these cancers. Now a new study from researchers at Fred Hutchinson Cancer Research Center shows how weight loss – through diet alone or diet and exercise – might change pro-cancer substances in the body.
The 12-month controlled trial of 439 healthy, postmenopausal women with overweight/obesity included 4 randomized groups: calorie restriction diet; moderate activity (goal of 3.75 hours per week), diet and exercise, and no intervention. Researchers wanted to see if these lifestyle changes would affect four substances in the body (biomarkers) that influence formation of blood vessels needed for tumor growth. Fat cell growth also requires a greater blood supply, so these biomarkers are also associated with increasing fat tissue.
The most recent Dietary Guidelines for Americans recommend the Mediterranean Diet as one way to eat healthfully. Yet pasta, a common food in this diet, is often seen as packing on the pounds. So scientists in Italy wanted to see if they could tease apart how pasta, as part of the Mediterranean diet, may affect a person’s weight and body shape.
That’s important for cancer risk, because understanding how the food you and your family eat every day affects weight is one important key to lower risk. AICR’s evidence shows that having too much body fat links to higher risk for eleven types of cancer, including colorectal, liver and postmenopausal breast.